Cannabinoids for chronic pain
نویسندگان
چکیده
منابع مشابه
Cannabinoids in chronic pain and palliative care.
BACKGROUND AND OBJECTIVES Several studies have focused on Cannabis sativa (Cs) due to its analgesic potential and its ability to alleviate symptoms of disorders of the central nervous system. However, since marijuana, one of its popular names, is the most common illicit drug throughout the world, it breeds prejudice both among lay people and health care professionals. The objective of this stud...
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To the Editor:—An article published by Holdcroft et al. in the May 2006 issue of ANESTHESIOLOGY reported the analgesic and adverse effects of an oral cannabis extract for postoperative pain management. To date, only three other manuscripts investigating the role of cannabinoids in postoperative pain have been published. The conclusions from these studies are that cannabinoids are not ideally su...
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Treatment options for neuropathic pain have limited efficacy and use is fraught with dose-limiting adverse effects. The endocannabinoid system has been elucidated over the last several years, demonstrating a significant interface with pain homeostasis. Exogenous cannabinoids have been demonstrated to be effective in a range of experimental neuropathic pain models, and there is mounting evidence...
متن کاملCannabinoids and neuropathic pain.
After a brief overview of the endocannabinoid system (CB receptors, and endocannabinoids) and of the cannabinergic ligands, some general issues related to cannabinoids and pain are commented. Finally, the most important findings regarding cannabinoids and neuropathic pain are discussed in detail.
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This article of the month presents results of a clinical study conducted in the UK and Romania, which evaluated the efficacy of a THC:CBD cannabis extract (Sativex®) and a THC cannabis extract in the treatment of 177 patients with cancer pain, who experienced inadequate pain reduction despite intake of opioids [Johnson et al. J Pain Symptom Manage, 2010, in press]. Sativex resulted in a signifi...
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ژورنال
عنوان ژورنال: BMJ
سال: 2008
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.39434.444583.80